In this study, we used a small implantable complementary metal–oxide–semiconductor (CMOS) imaging device developed by our research group to estimate the blood flow changes by focus...

Development of direct neural interface (DNI) including visual prostheses absolutely requires confirmation of their long-term safety and stability. Functional evaluation by electric...

Diffuse correlation spectroscopy (DCS) is an emerging optical technique for noninvasive measurement of hemodynamics of living tissues. Using emitter and detector optical probes att...

Bronchoscopic diagnosis of peripheral lung cancer with ground-glass opacity (GGO) is difficult because GGO lesions cannot be visualized using currently available radial probe endob...

Two different experiments utilizing the motor imagery of finger movement were conducted. We attempted to reveal the difference in corticospinal excitability between tonic contracti...

It has been shown that injection of a minute electrical noise to an afferent input enhances the steadiness of force output, while reducing the variability of motor unit discharge i...

In this study, we improved upon a high-input impedance monitoring device comprising capacitive sheet electrodes placed under a bed sheet, aiming to detect all ECG waves including T...

Surgery can become safer and more reliable if the conditions of the organs can be physically and quantitatively assessed through simultaneous intraoperative measurements and physic...

Bipedal locomotion requires an automatic process for rhythmic motor generation, as well as volitional and precise motor control for purposeful action. The neural substrates for the...

We have developed retinal prosthetic devices based on suprachoroidal-transretinal stimulation (STS). The effectiveness and safety of such novel devices are confirmed by in vitro an...

We have developed a novel electronic musical instrument with a pre-programmed score, called “Cymis,” to help the disabled enjoy playing musical pieces. In 2008, eld experiments co...

Spatial control of cell position is essential for numerous studies in tissue engineering, such as generation of linearly patterned muscle tissues, radially patterned liver lobule t...

Implantable neural stimulators have recently attracted attention because of their potential applicability to the treatment of sensory neural disorders such as hereditary hearing lo...

The dynamics of dehydroepiandrosterone (DHEA) and cortisol secretion from sleep through awakening were examined by collecting and analyzing saliva samples using a novel method. Six...

An increasing number of closed-loop blood glucose (BG) control algorithms have been developed in recent years with the ‘articial pancreas’ as the ultimate goal, although tight pos...

The dialysis fluid flow and solute removal performance of newly developed dialyzers and a downsized dialyzer were evaluated using a dimensionless correlation equation related to th...

Melanoma is a malignant tumor occurring typically in the skin. Advanced melanoma has very poor prognosis, and is also called the “king of cancer”. On the other hand, early-stage me...

Good mass transfer and high cell density culture are required for bioreactors using animal cells. These criteria can be met by fabricating a tissue in the bioreactor. In the presen...

Ventricular activation time (AT [ms]) is the time required to activate the ventricle electrically. The influences of AT on hemodynamics are of interest in clinical studies on metho...

To relieve or manage stress, objective assessment of stress is required. Instead of direct assessment of stress, we have been investigating whether responses to emotional stimuli a...