Bipedal locomotion requires an automatic process for rhythmic motor generation, as well as volitional and precise motor control for purposeful action. The neural substrates for the...

We have developed retinal prosthetic devices based on suprachoroidal-transretinal stimulation (STS). The effectiveness and safety of such novel devices are confirmed by in vitro an...

We have developed a novel electronic musical instrument with a pre-programmed score, called “Cymis,” to help the disabled enjoy playing musical pieces. In 2008, eld experiments co...

Spatial control of cell position is essential for numerous studies in tissue engineering, such as generation of linearly patterned muscle tissues, radially patterned liver lobule t...

Implantable neural stimulators have recently attracted attention because of their potential applicability to the treatment of sensory neural disorders such as hereditary hearing lo...

The dynamics of dehydroepiandrosterone (DHEA) and cortisol secretion from sleep through awakening were examined by collecting and analyzing saliva samples using a novel method. Six...

An increasing number of closed-loop blood glucose (BG) control algorithms have been developed in recent years with the ‘articial pancreas’ as the ultimate goal, although tight pos...

The dialysis fluid flow and solute removal performance of newly developed dialyzers and a downsized dialyzer were evaluated using a dimensionless correlation equation related to th...

Melanoma is a malignant tumor occurring typically in the skin. Advanced melanoma has very poor prognosis, and is also called the “king of cancer”. On the other hand, early-stage me...

Good mass transfer and high cell density culture are required for bioreactors using animal cells. These criteria can be met by fabricating a tissue in the bioreactor. In the presen...

Ventricular activation time (AT [ms]) is the time required to activate the ventricle electrically. The influences of AT on hemodynamics are of interest in clinical studies on metho...

To relieve or manage stress, objective assessment of stress is required. Instead of direct assessment of stress, we have been investigating whether responses to emotional stimuli a...

A simple time-lapse cinematography (TLC) device was developed to enable detection, at the cleavage stages, of embryos that have the potential to develop into high-scoring blastocys...

Sweating, the intermittent secretion of fluid from the sweat glands, is an indispensable mechanism for the regulation of body temperature. The methods used to measure the sweat rat...

In recent years, surgeries requiring high surgical skills – including laparoscopic surgery and function-preserving surgery – are being more commonly conducted, which has led to the...

Moving-mask lithography with backside exposure was utilized to generate master male mold for biodegradable polymer microneedle production. The microneedle shape was calculated from...

By integrating locally operated, small surgical robots and devices, a surgeon can perform, robotically assisted laparoscopic surgery safely and accurately. However, no locally oper...

In brain function measurements by near-infrared spectroscopy, improving the measurement accuracy and expanding the measurement region are important for analyzing brain functional c...

Alpha-band (8–13 Hz) rhythm during encoding of sequentially presenting memory items was recorded using a 76-channel magnetoencephalograph. In a memory task, seven images each with ...

Scale parameters are used to combine two or more models in different scales into one integrative model. One of the crucial issues in the research field of biosimulation in hemodyna...