A heart model that can be expressed mathematically in a computer is desirable. Heart modeling applications can be classified into four areas : clinical, research, educational, and ...

The number of elderly individuals in need of care is increasing with the growing elderly population in Japan, resulting in the increased production of disposable diapers. Several w...

In this study we investigated the cerebral correlation of computer-and paper-based neuropsychological tests commonly used as measures of frontal lobe function. Functional magnetic ...

Immature neovessels in tumors lead to the formation of heterogeneous hypoxic areas within tumors. Such hypoxic conditions not only reduce the effectiveness of radiation treatment b...

The implantable cardioverter-defibrillator is an effective therapeutic device for preventing death from life-threatening arrhythmias such as ventricular tachycardia and ventricular...

Specialized languages used for describing computational models in the field of systems biology and physiology, such as Systems Biology Markup Language (SBML), CellML, and Physiolog...

To date, no method is available to quantify jerk at a local point of the human joint along a direction that depends on the 3D curvature of the articular surface. This paper propose...

When magnetic nanoparticles (MNPs) are used as a contrast agent for magnetic particle imaging (MPI), they are rapidly excreted during systemic circulation by the reticuloendothelia...

This paper provides a 3D ultrasound navigation system with a blood vessel network (BVN) reconstruction algorithm for microbubble delivery therapy, which manipulates microbubbles in...

Bubble liposomes (BLs), which are gas-encapsulated liposomes several hundred nanometers in diameter, are expected to be developed as a novel tool for gene and drug delivery using u...

Knowing the mechanical characteristics of organs during surgery ensures effective diagnosis and treatment. A surgeon's hand can sense the characteristics of organs in open abdomina...

Spatio-temporal reconstruction methods for positron emission tomography estimate the tissue time-activity curves that are required for functional imaging. Since the time-related ch...

The objective of this study was to examine the validity of estimating cell number using the water-soluble tetrazolium salts-8 (WST-8) assay for normal cells. The changes in mitocho...

Hypoxia-related mechanisms are important in tumor biology and immune responses. Oxygen is delivered to tumor tissue by blood flowing through abnormal and dysfunctional microvessels...

We developed a technique to evaluate mental fatigue quantitatively by measuring perceptual performance of visually presented flicker;namely, the flicker-perception threshold (FPT),...

Although immobilization of growth factors (GFs) on culture substrates has been investigated as a cell culture technique, quantification of the bioactive stability of immobilized GF...

As a conventional hospital information system (HIS) requires clinical staff to record data, the introduction of an HIS deprives those staff of time for direct treatment and care. T...

This paper provides a robotic ultrasound transducer positioning system for minimally invasive ultrasonic therapy by manipulating microbubbles in blood vessel, aiming at effective h...

Human movements measured by a motion capture system are often represented by the motions of a multi-rigid link model of the body, which allows mechanodynamic analysis of the moveme...

Compared to the evaluation of new pharmaceutical drugs, the assessments of the design and results of clinical trials for medical devices are not well established. For medical devic...