When magnetic nanoparticles (MNPs) are used as a contrast agent for magnetic particle imaging (MPI), they are rapidly excreted during systemic circulation by the reticuloendothelia...

This paper provides a 3D ultrasound navigation system with a blood vessel network (BVN) reconstruction algorithm for microbubble delivery therapy, which manipulates microbubbles in...

Bubble liposomes (BLs), which are gas-encapsulated liposomes several hundred nanometers in diameter, are expected to be developed as a novel tool for gene and drug delivery using u...

Knowing the mechanical characteristics of organs during surgery ensures effective diagnosis and treatment. A surgeon's hand can sense the characteristics of organs in open abdomina...

Spatio-temporal reconstruction methods for positron emission tomography estimate the tissue time-activity curves that are required for functional imaging. Since the time-related ch...

The objective of this study was to examine the validity of estimating cell number using the water-soluble tetrazolium salts-8 (WST-8) assay for normal cells. The changes in mitocho...

Hypoxia-related mechanisms are important in tumor biology and immune responses. Oxygen is delivered to tumor tissue by blood flowing through abnormal and dysfunctional microvessels...

We developed a technique to evaluate mental fatigue quantitatively by measuring perceptual performance of visually presented flicker;namely, the flicker-perception threshold (FPT),...

Although immobilization of growth factors (GFs) on culture substrates has been investigated as a cell culture technique, quantification of the bioactive stability of immobilized GF...

As a conventional hospital information system (HIS) requires clinical staff to record data, the introduction of an HIS deprives those staff of time for direct treatment and care. T...

This paper provides a robotic ultrasound transducer positioning system for minimally invasive ultrasonic therapy by manipulating microbubbles in blood vessel, aiming at effective h...

Human movements measured by a motion capture system are often represented by the motions of a multi-rigid link model of the body, which allows mechanodynamic analysis of the moveme...

Compared to the evaluation of new pharmaceutical drugs, the assessments of the design and results of clinical trials for medical devices are not well established. For medical devic...

Autologous bone grafts are used to reconstruct mandibular bone defects because autologous bone is highly osteogenic and does not elicit immune reactions. Because harvesting these...

The technique of mesoscopic epifluorescence tomography (MEFT) has been reported previously. Although it allows three-dimensional (3D) imaging of the concentration distribution of f...

Cationic lipoplexes, which consist of cationic lipids and DNA, are widely used in gene transfection. Recently, some reports suggest that the transfection efficiency of lipoplexes i...

We investigated the effects of forced response-like movements on serial reversal learning of a sensorimotor task in normal and hemiplegic (unilateral cortical lesion in the forepaw...

A functional magnetic resonance imaging (fMRI) method that focuses on neural magnetic fields has great potential to detect neural activities more directly than the conventional met...

Auditory steady-state responses (ASSR) to sinusoidal amplitude-modulated (SAM) tones or to repeated clicks presented at rates between 10 and 70Hz have been recorded since the 1980'...

Functional magnetic resonance imaging (fMRI) is one of the techniques capable of detecting human brain function noninvasively. Although many fMRI studies have adopted echo-time (TE...